Disturbances of long-term memory in aphasic patients. A comparison of anterior and posterior lesions.
Disturbances of long-term memory in aphasic patients. A comparison of anterior and posterior lesions.
复制标题
失语症患者的长期记忆障碍。
DOI：
10.1093/brain/107.2.605
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发表时间：
1984
期刊：
影响因子：
--
通讯作者：
Jordan,LS
中科院分区：
文献类型：
--
作者：
Risse,GL;Rubens,AB;Jordan,LS
根据 CT 扫描记录，检查了 20 名失语症患者在语言列表学习任务中的表现与病变部位的关系。额下叶和/或基底神经节病变的患者在列表的获取和长期保留方面均严重受损，而后颞顶受累的患者的表现几乎正常。这些结果与同一患者组的短期记忆测试分数形成鲜明对比，显示出相反的趋势。这些发现支持短期和长期记忆系统的功能和神经解剖学分离，并表明下额叶和基底神经节的神经连接可能对于启动检索过程至关重要。
The performance of 20 aphasic patients on a verbal list-learning task was examined in relation to site of lesion, as documented by CT scan. Patients with lesions of the inferior frontal lobe and/or the basal ganglia were severely impaired in both acquisition and long-term retention of the list, while the performance of patients with posterior temporoparietal involvement was nearly normal. These results contrasted sharply with scores on short-term memory tests by the same patient groups which showed an opposite trend. The findings support a functional and neuroanatomical dissociation of short and long-term memory systems and suggest that neural connections of the inferior frontal lobe and the basal ganglia may be crucial for initiating the retrieval process.