Large epidemics of hemorrhagic fevers in Mexico 1545-1815

Large epidemics of hemorrhagic fevers in Mexico 1545-1815
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DOI:
10.4269/ajtmh.2000.62.733
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发表时间:
2000-06-01
影响因子:
3.3
通讯作者:
Maguire, JH
Maguire, JH
中科院分区:
医学4区
文献类型:
--
作者:
Acuna-Soto, R;Romero, LC;Maguire, JH

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1545年,也就是西班牙征服阿兹特克帝国24年后,墨西哥高地出现了一种恶性出血热。该疾病的特征是高烧、头痛、鼻、耳、口出血,伴有黄疸、剧烈腹痛和胸痛以及急性神经系统症状。这种疾病是高度致命的,持续三到四天。它主要攻击当地居民,使西班牙人几乎不受影响。出血热在该地区持续了三个世纪,病原体仍然未知。在这份报告中,我们描述了,现在有更多的信息,分析了殖民时期在墨西哥发生的四次流行病,重点是1576年的流行病,造成墨西哥45%的人口死亡。重要的是,要从纯粹的历史背景中回顾这些疾病及其造成的流行病,并考虑到如果它们再次出现,它们具有潜在的危险性这一现实。
In 1545, twenty-four years after the Spanish conquest of the Aztec empire, an epidemic of a malignant form of a hemorrhagic fever appeared in the highlands of Mexico. The illness was characterized by high fever, headache, and bleeding from the nose, ears, and mouth, accompanied by jaundice, severe abdominal and thoracic pain as well as acute neurological manifestations. The disease was highly lethal and lasted three to four days. It attacked primarily the native population, leaving the Spaniards almost unaffected. The hemorrhagic fevers remained in the area for three centuries and the etiologic agent is still unknown. In this report we describe, and now that more information is available, analyze four epidemics that occurred in Mexico during the colonial period with a focus on the epidemic of 1576 which killed 45% of the entire population of Mexico. It is important to retrieve such diseases and the epidemics they caused from their purely historical context and consider the reality that if they were to reemerge, they are potentially dangerous.