Antibacterial study and fatty acid analysis of lipids of the sponge Myrmekioderma granulata
Antibacterial study and fatty acid analysis of lipids of the sponge Myrmekioderma granulata
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DOI：
10.1007/s10600-009-9445-4
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发表时间：
2009-11
影响因子：
0.8
通讯作者：
Pravat Manjari Mishra;A. Sree;Sasmita Baliarsingh
中科院分区：
文献类型：
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作者：
Pravat Manjari Mishra;A. Sree;Sasmita Baliarsingh
本文研究了从奥里萨邦孟加拉湾13 m深处采集的海绵Myrmekiagrulata（Escherichia）的亲脂性提取物的组成。鉴定了脂肪酸以及挥发物和固醇。首次沿着从该物种中鉴定出4，8，12-三甲基十三烷酸和重要的多不饱和脂肪酸，如亚油酸（n-6，C18：2）、二高-γ-亚麻酸（n-6，C20：3）、5，8，11，14-二十碳四烯酸（n-3，C20：4）和5，8，11，14，17-二十碳五烯酸（EPA）（n-3，C20：5）。通过GC-MS鉴定了支链多不饱和脂肪酸如br-C26：2，25-甲基-5，9-二十七碳二烯酸和24-甲基-5，9-二十七碳二烯酸。
The composition of the lipophilic extract of the spongeMyrmekioderma granulata(Esper) collected from 13 m depth of the Bay of Bengal of the Orissa coast was investigated. Fatty acids as well as volatiles and sterols were identified. 4,8,12-Trimethyltridecanoic acid was identified for the first time along with the important PUFAs such as linoleic acid (n-6, C18:2), dihomo-γ-linolenic acid (n-6, C20:3), 5,8,11,14-eicosatetraenoic acid (n-3, C20:4), and 5,8,11,14,17-eicosapentaenoic acid (EPA) (n-3, C20:5) from this species. The branched polyunsaturated fatty acids like br-C26:2, 25-methyl-5,9-heptacosadienoic acid and 24-methyl-5,9heptacosadienoic acid were also identified by GC-MS. The lipid extract exhibited limited activity against different pathogens.