Biopsychosocial Attributes of Single-region and Multi-region Body Pain During Early Adolescence: Analysis of the ABCD Cohort.
Biopsychosocial Attributes of Single-region and Multi-region Body Pain During Early Adolescence: Analysis of the ABCD Cohort.
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DOI：
10.1097/ajp.0000000000001069
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发表时间：
2022-11-01
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目的：青春期多部位疼痛与较高的症状负担和较低的生活质量相关。本研究的目的是描述和比较健康的年轻adolescents.Materials和方法之间的单区域和多区域疼痛的生物心理社会属性：我们分析了10,320名儿童年龄在10.6至14岁的青少年大脑和认知发展研究中自我报告的疼痛。结果：五分之一的青少年表示近期有多个部位疼痛。当心理和社会文化因素被添加到疼痛的生物模型中时，序贯回归支持改进的模型拟合;然而，这些模型改进了多区域而不是单区域疼痛的分类。性别和青春期的显著相互作用效应在各模型中保持不变，与青春期前相比，两种性别在每个青春期进展阶段的疼痛几率增加，但在青春期后期女孩和男孩之间无差异（校正比值比[OR]= 2.45 [1.72，3.49]和校正OR= 1.63 [1.20，2.23]）。心理因素改善了多区域疼痛的分类，其中焦虑、躯体症状和嗜睡具有显著影响。最后，与白色和非西班牙裔儿童相比，黑人和西班牙裔儿童报告疼痛的可能性较小（校正OR= 0.70 [0.61，0.80];校正OR= 0.88 [0.78，0.99]），但疼痛时疼痛干扰显著更高（校正OR= 1.49 [1.29，1.73]和校正OR= 1.20 [1.06，1.35]）。讨论：疼痛是一种生物心理社会现象，但心理和社会文化特征可能更相关的多区域相比，单区域疼痛在青春期早期。
Objectives:Multi-region pain during adolescence is associated with a higher symptom burden and lower quality of life. The purpose of this study was to describe and compare the biopsychosocial attributes of single-region and multi-region pain among healthy young adolescents.Materials and Methods:We analyzed data from 10,320 children aged 10.6 to 14 years who self-reported pain in the Adolescent Brain and Cognitive Development Study. Pain was coded as single-region or multi-region based on body map data.Results:One in 5 young adolescents indicated recent multi-region pain. Sequential regression supported improved model fit when psychological and sociocultural factors were added to a biological model of pain; however, these models improved the classification of multi-region but not single-region pain. A significant interaction effect of sex and puberty remained constant across models with increased odds of pain at each advancing pubertal stage for both sexes compared with prepuberty, but no difference between girls and boys at late puberty (adjusted odds ratio [OR]= 2.45 [1.72, 3.49] and adjusted OR= 1.63 [1.20, 2.23], respectively). Psychological factors improved the classification of multi-region pain with significant effects of anxiety, somatic symptoms, and somnolence. Finally, compared with White and non-Hispanic children, Black and Hispanic children were less likely to report pain (adjusted OR= 0.70 [0.61, 0.80]; adjusted OR= 0.88 [0.78, 0.99], respectively) but had significantly higher pain interference when pain was present (adjusted OR= 1.49 [1.29, 1.73] and adjusted OR= 1.20 [1.06, 1.35], respectively).Discussion:Pain is a biopsychosocial phenomenon, but psychological and sociocultural features may be more relevant for multi-region compared with single-region pain during early adolescence.