D-psicose is a rare sugar that provides no energy to growing rats

D-psicose is a rare sugar that provides no energy to growing rats
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DOI:
10.3177/jnsv.48.77
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发表时间:
2002-02-01
影响因子:
1.6
通讯作者:
Izumori, K
Izumori, K
中科院分区:
医学4区
文献类型:
--
作者:
Matsuo, T;Suzuki, H;Izumori, K

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D-阿洛酮糖 (D-ribo-2-hexulose) 是 D-果糖的 C-3 差向异构体,少量存在于商业碳水化合物复合物和农产品中。我们之前曾报道过,饮食中添加 D-阿洛酮糖可抑制肝脏脂肪生成酶的活性。喂食 D-阿洛酮糖的大鼠脂肪积累较低可能是由于肝脏中脂肪生成较低。本研究检查了 D-阿洛酮糖中可用于大鼠生长的能量。雄性Wistar大鼠每天接受7克基础饮食,其中添加固定量的蔗糖、D-果糖或D-阿洛酮糖(0.5-2.0克),持续20天。体重增加和身体能量增加随着蔗糖和 D-果糖的增加而增加,但随着 D-阿洛酮糖的增加而增加。一克蔗糖、D-果糖和 D-阿洛酮糖分别产生 2.29、1.76 和 0.007 kcal 的净能量增益。 D-阿洛酮糖的能量沉积效率是蔗糖的0.3%。 D-阿洛酮糖的能量值实际上为零。这些结果表明,D-阿洛酮糖是一种稀有的零能量糖,可用作肥胖者的甜味剂,有助于减肥。
D-Psicose ( D-ribo-2-hexulose), a C-3 epimer Of D-fructose, is present in small quantities in commercial carbohydrate complexes and agricultural products. We have previously reported that D-psicose supplements in diets suppressed hepatic lipogenic enzyme activity. The lower fat accumulation in rats fed D-psicose may be due to lower lipogenesis in the liver. The present study examined the energy available in D-psicose for rat growth. Male Wistar rats received 7 g daily of a basal diet to which fixed amounts of sucrose, D-fructose, or D-psicose (0.5-2.0 g) were added for 20 d. Body weight gain and body energy gain increased with increases in sucrose and D-fructose, but not with D-psicose. One gram of sucrose, D-fructose, and D-psicose produced a net energy gain of 2.29, 1.76, and 0.007 kcal, respectively. The efficiency of energy deposition from D-psicose was 0.3% that of sucrose. The energy value Of D-psicose was effectively zero. These results suggest that D-psicose is a rare sugar providing zero energy that may be useful in sweeteners for obese people as an aid for weight reduction.