Usefulness of filtered unipolar electrogram morphology for evaluating transmurality of ablated lesions during pulmonary vein isolation.
Usefulness of filtered unipolar electrogram morphology for evaluating transmurality of ablated lesions during pulmonary vein isolation.
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DOI：
10.1016/j.joa.2015.10.001
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发表时间：
2016-04
影响因子：
2
通讯作者：
Hirayama A
中科院分区：
文献类型：
--
作者：
Kogawa R;Watanabe I;Okumura Y;Mano H;Sonoda K;Nagashima K;Sasaki N;Ohkubo K;Takahashi K;Iso K;Kurokawa S;Nakai T;Hirayama A
虽然双极电图的振幅和形态的变化被广泛地用作消融效应的指导，但关于单极电图的信息很少。比较肺静脉隔离期间心房颤动患者滤过双极（BP）和滤过单极（UP）电图的振幅和形态。记录6例房颤患者肺静脉窦各消融点消融前后的BP （30 ~ 250 Hz）和UP （30 ~ 100 Hz）信号。在消融术前血压电位低幅值（<0.5 mV）的电图组中，消融术后UP电位的降幅明显大于BP电位，而在血压电位高幅值（≥0.5 mV）的电图组中，两种记录方法之间的降幅相似。此外，消融后无起搏部位的UP电图S波消失，而BP电图未见特征性形态学改变。过滤后的向上电图可用于评估病变形成的有效性。
Although alteration of the amplitude and morphology of bipolar electrograms is used widely as a guide of the ablation effect, there is little information concerning unipolar electrograms. The amplitude and morphology of filtered bipolar (BP) and filtered unipolar (UP) electrograms were compared during pulmonary vein isolation in patients with atrial fibrillation. BP (30–250 Hz) and UP (30–100 Hz) signals from the ablation catheter were recorded before and after each ablation point at the pulmonary vein antrum in 6 patients with atrial fibrillation. In the electrogram group with low-voltage amplitude in BP electrograms before ablation (<0.5 mV), the reduction in amplitude after ablation was significantly greater in the UP than in the BP electrograms, whereas the reduction was similar between the two recording methods in the electrogram group with high-voltage amplitude in BP electrograms (≥0.5 mV). Furthermore, the S wave in the UP electrograms disappeared at the sites of no pace capture after ablation, whereas no characteristic morphologic changes were observed in the BP electrograms. Filtered UP electrograms may be useful in assessing the effectiveness of lesion formation.