An Evaluation of the Diabetic Kidney Disease Definition in Chinese Patients Diagnosed with Type 2 Diabetes Mellitus
An Evaluation of the Diabetic Kidney Disease Definition in Chinese Patients Diagnosed with Type 2 Diabetes Mellitus
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DOI：
10.1177/147323000903700526
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发表时间：
2009-09-01
影响因子：
1.6
通讯作者：
Hu, R.
中科院分区：
文献类型：
--
作者：
Lu, B.;Gong, W.;Hu, R.
视网膜病变的伴随存在可能有助于区分2型糖尿病的肾脏病理。本横断面研究通过比较中国2型糖尿病患者（n = 668）不同亚组中糖尿病视网膜病变的发生率，评价了预测糖尿病肾病（DKD）患者可能性的能力。患者中慢性肾脏疾病的患病率为63.3%（6.6%为DKD，41.0%为可能的DKD，15.7%为非糖尿病肾病[NDRD]）。DKD组中糖尿病视网膜病变患者的百分比（63.6%）显著高于可能DKD组（24.9%）和NDRD组（19.0%）。Logistic回归分析显示DKD与糖尿病视网膜病变独立相关。美国国家肾脏基金会-肾脏疾病结局质量倡议（TM）定义的DKD发生可能性适用于中国糖尿病患者。糖尿病视网膜病变在DKD患者中的患病率高于可能患有DKD或NDRD的患者。
The concomitant presence of retinopathy may be helpful in discriminating kidney pathology in type 2 diabetes. This cross-sectional study evaluated the ability to predict the likelihood of patients having diabetic kidney disease (DKD) by comparing the percentage incidence of diabetic retinopathy in different subgroups of Chinese patients with type 2 diabetes (n = 668). The prevalence of chronic kidney disease in the patients was 63.3% (6.6% with DKD, 41.0% with possible DKD and 15.7% with non-diabetic renal disease [NDRD]). The percentage of patients with diabetic retinopathy in the DKD group (63.6%) was significantly higher than in the possible DKD group (24.9%) and the NDRD group (19.0%). DKD was independently associated with diabetic retinopathy based on logistic regression analysis. The likelihood of DKD occurrence as defined by the National Kidney Foundation-Kidney Disease Outcomes Quality Initiative (TM) of the USA is applicable to Chinese patients with diabetes. Diabetic retinopathy was more prevalent in patients with DKD compared with patients with possible DKD or NDRD.