Psychiatric referral and glycemic control of Egyptian type 2 diabetes mellitus patients with depression
Psychiatric referral and glycemic control of Egyptian type 2 diabetes mellitus patients with depression
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DOI：
10.1016/j.genhosppsych.2016.01.002
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发表时间：
2016-05-01
影响因子：
7
通讯作者：
Abdel-Moety, Hanaa
中科院分区：
文献类型：
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作者：
Fawzi, Mounir H.;Said, Nagwa S.;Abdel-Moety, Hanaa
目的：评估埃及 2 型糖尿病 (T2DM) 合并抑郁症患者精神科转诊接受氟西汀治疗与血糖控制之间的关系。 方法：为 2013 年 5 月至 2015 年 4 月期间在埃及 Zagazig 大学医院糖尿病门诊就诊且重性抑郁量表 (MDI) 筛选得分≥ 20 的 T2DM 患者 (n=196) 提供精神科转诊接受氟西汀治疗和监测。下降者 (56.1%) 通过糖尿病专家就诊（注意力控制）接受时间/注意力匹配的护理。在给予氟西汀时（T1）和8周后（T2）对氟西汀患者和对照进行比较。在线性回归分析中使用与血糖控制显着相关的因素作为自变量。结果：86 名患者 (43.9%) 接受了精神病转诊。他们中的大多数（97.7%）在整个研究过程中仍然坚持氟西汀（平均每日剂量= 31.9 mg）。在 T2 时，与对照组相比，这些患者的 MDI、空腹血糖和糖化血红蛋白 (HbA1c) 水平较基线有所降低（所有比较的 P
Objective: To evaluate the relationship between psychiatric referral acceptance for fluoxetine treatment and glycemic control in type 2 diabetes mellitus (T2DM) Egyptian patients with depression.Methods: Patients with T2DM who attended the diabetes outpatients clinic at Zagazig University Hospital, Egypt, between May 2013 and April 2015 and who scored >= 20 on screening with the Major Depression Inventory (MDI) (n=196) were offered a psychiatric referral for fluoxetine treatment and monitoring. Decliners (56.1%) received time/attention matched care via diabetologist visits (attentional controls). Fluoxetine patients and controls were compared at the time of the offer (T1) and 8 weeks later (T2). Factors that significantly correlated with glycemic control were used in a linear regression analysis as the independent variables.Results: Eighty-six patients (43.9%) accepted psychiatric referral. Most of them(97.7%) remained throughout the study adherent to fluoxetine (mean daily dose=31.9 mg). At T2, these patients, in comparison to controls, showed a reduction from baseline in MDI, fasting plasma glucose and glycosylated hemoglobin (HbA1c) levels (P for all comparisons