Developmental biology in Geneva: a three century-long tradition.
Developmental biology in Geneva: a three century-long tradition.
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日内瓦的发育生物学：三个世纪之久的传统。
DOI：
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发表时间：
2002
影响因子：
0.7
通讯作者：
D. Duboule
中科院分区：
文献类型：
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作者：
M. Buscaglia;D. Duboule
18世纪上半叶，生命科学在独立的日内瓦共和国开始蓬勃发展。然而，在那个时代很难确定一个真正的发育生物学家流派。尽管如此，在过去的两个半世纪中，几位杰出的科学家已经建立并保持了胚胎发育和生殖研究的强大传统。在这篇简短的历史叙述中，我们简要地向这些著名的先驱者致敬，强调他们工作的原创性和质量，以及许多随之而来的概念和方法论的进步。我们从亚伯拉罕·特雷布利（Abraham Trembley，1710-1784）和九头蛇和再生的发现开始，还有查尔斯·博内特（Charles Bonnet，1720-1793），他的贡献之一是首先观察到孤雌生殖的发育。 19世纪，卡尔·沃格特（Carl Vogt，1817-1895）和爱德华·克拉帕雷德（Edouard Claparède，1832-1871）是该研究领域的著名科学家，而赫尔曼·福尔（Hermann Fol，1845-1892）通过对受控鸡的横向不对称性进行实验，即使不是因果胚胎学的创始人，也可以被视为先驱之一。最近，埃米尔·居耶诺（Emile Guyénot，1885-1963）和基蒂·庞斯（Kitty Ponse，1897-1982）延续了这一传统，如今在加尔文市依然盛行。
It was in the first half of the 18th century when life sciences started to flourish in the independent republic of Geneva. However, it is difficult to identify a genuine school of developmental biologists during that era. Nevertheless, several prominent scientists over the past two and a half centuries have established and maintained a strong tradition of studies in embryological development and reproduction. In this short historical account, we briefly pay tribute to these famous forerunners, by emphasizing both the originality and quality of their work, as well as the many accompanying conceptual and methodological advances. We start with Abraham Trembley (1710-1784) and the discovery of Hydra and of regeneration, and with Charles Bonnet (1720-1793) who, amongst other contributions, first observed parthenogenetic development. In the 19th century, Carl Vogt (1817-1895) and Edouard Claparède (1832-1871) were well-known scientists in this field of research, whereas Hermann Fol (1845-1892) can be considered as one of the pioneers, if not the founder, of causal embryology, through his experiments on lateral asymmetry in manipulated chicken. More recently, Emile Guyénot (1885-1963) and Kitty Ponse (1897-1982) perpetuated this tradition, which is well alive nowadays in the city of Calvin.