Thermoluminescent dosimetry of the Symmetra 125I model I25.S06 interstitial brachytherapy seed.

Thermoluminescent dosimetry of the Symmetra 125I model I25.S06 interstitial brachytherapy seed.
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Symmetra 125I 型号 I25.S06 间质近距离放射治疗种子的热释光剂量测定。

DOI:
10.1118/1.1388218
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发表时间:
2001
期刊:
影响因子:
3.8
通讯作者:
Harrison,LB
Harrison,LB
中科院分区:
医学3区
文献类型:
--
作者:
Patel,NS;Chiu-Tsao,ST;Williamson,JF;Fan,P;Duckworth,T;Shasha,D;Harrison,LB

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随着近距离放射治疗前列腺治疗的疗效逐渐被认识到,新的种子模型正在被引入。在这篇文章中,我们介绍了一种新设计的种子(UroMed/Bebig Symmetra™,型号I25.S06)在固体水体模中的热释光剂量测定(EAI)。将来自Bicron(Solon,OH)的尺寸为LiF 100的立方块在距晶种的各种距离处以10°增量的0°至90°范围内的角度照射。通过在远距离治疗束中照射来校准探测器。蒙特卡罗模拟用于解释TLD能量依赖性以及固体水成分(通过样品的化学分析确定)与液态水的偏差。根据可追溯至1999年NIST标准的校准(针对1999年NIST测量错误进行了校正),确定了每单位空气比释动能强度的剂量率。剂量数据以TG-43格式表示,作为距离和角度的函数。Λ的值, 和各向异性常数,以用于放射治疗计划(RTP)软件。确定剂量率常数与型号6702相当,高于型号6711。我们发现Symmetra™粒子的相对剂量分布与型号6702相似,各向异性小于型号6711。考虑到测量的固体水组成与制造商质量标准的偏差后,发现重复测量结果与蒙特卡罗辅助值之间具有良好的一致性。
As the efficacy of brachytherapy prostate treatment is becoming realized, new models of seeds are being introduced. In this article we present thermoluminescent dosimetry (TLD) in a solid water phantom for a new design of seed (UroMed/Bebig Symmetra™, Model I25.S06). TLD cubes, LiF TLD‐100, from Bicron (Solon, OH) with dimension were irradiated at various distances from the seed at angles ranging from 0° to 90° in 10° increments. The TLD detectors were calibrated by irradiation in a teletherapy beam. Monte Carlo simulation was used to account for TLD energy dependence and the deviation of solid water composition (as determined by chemical analysis of a sample) from liquid water. Dose rates per unit air kerma strength were determined based on calibrations traceable to the 1999 NIST standard (corrected for NIST measurement errors made in 1999) for the Symmetra™ seed. Dose data is presented in TG‐43 format as a function of distance and angle. Values for Λ, and the anisotropy constant are obtained for use in radiation treatment planning (RTP) software. The dose rate constant was determined to be which is comparable to model 6702 and higher than model 6711. We find the relative dose distributions of the Symmetra™ seed are similar to model 6702, and less anisotropic than model 6711. After accounting for deviation of measured solid water composition from the manufacturer's specification, good agreement between TLD results and Monte‐Carlo‐aided values was found.
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DOI: --
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发表时间: 1998
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