Load force during manual transport in Parkinson's disease
Load force during manual transport in Parkinson's disease
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DOI：
10.1111/j.1600-0404.2004.00243.x
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发表时间：
2004-06-01
影响因子：
3.5
通讯作者：
Steg, G
中科院分区：
文献类型：
--
作者：
Guo, X;Hosseini, N;Steg, G
目的：探索帕金森病（PD）患者日常生活活动中上肢灵活性的生理学测量方法。材料和方法-我们检查了7例PD患者和10例健康对照者在手动运输过程中的负载力输出。PD患者在未用药和用药状态下进行测量。测试运动包括两个连续的子运动：物体从工作台到支架的向上向前运输，以及物体从支架到工作台的向下向后运输。使用光电摄像机记录手部运动，并使用安装在测试对象中的力传感器测量负载力。结果-与对照组相比，PD患者具有不同的负荷力输出模式，其特征在于较慢的力发展和释放，较低的峰值力，以及运动过程中较少的动态力产生。用药后，患者的力量发展速度和峰值力量水平增加。结论：这些发现表明帕金森病损害了预编程运动的产生。在PD患者中观察到的运动可能是由于更多地依赖于反馈机制的代偿策略。
Objective - To search for a physiological method for the measurement of upper extremity dexterity during activities of daily life in Parkinson's disease (PD). Materials and methods - We examined load force output during manual transport in seven patients with PD and 10 healthy controls. PD patients were measured in both the non-medicated and medicated states. The test movement included two continuous sub-movements: an upward-forward transport of an object from the table to the stand, and a downward-backward transport of the object from the stand to the table. Hand movements were recorded using an optoelectronic camera, and load force was measured using a force sensor installed in the test object. Results - Compared with the controls, PD patients had a different pattern of load force output characterized by slower force development and release, lower peak force, and less dynamic force generation during movement. After medication, the speed of force development and the level of peak force increased in the patients. Conclusions - These findings suggest that PD impairs the production of preprogrammed movements. The movements observed in the PD patients may result from compensatory strategies relying more on feedback mechanisms.