Survival of very preterm infants admitted to neonatal care in England 2008-2014: time trends and regional variation
Survival of very preterm infants admitted to neonatal care in England 2008-2014: time trends and regional variation
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DOI：
10.1136/archdischild-2017-312748
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发表时间：
2018-05-01
影响因子：
4.4
通讯作者：
Modi, Neena
中科院分区：
文献类型：
--
作者：
Santhakumaran, Shalini;Statnikov, Yevgeniy;Modi, Neena
目的分析接受新生儿护理的极早产儿的生存趋势和地区差异。设置英格兰所有新生儿单位。患者2008 - 2014年出生于22（+0）-31（+6）周（+天）胎龄（GA）并接受新生儿护理的婴儿; 1995年和2006年出生22（+0）-25（+6）周（+天）的新生儿和2013年出生22（+0）-31（+6）周（+天）的活产婴儿的已发表数据。我们使用逻辑回归模型的生存概率与出生体重，GA，性别，产前类固醇暴露和多胎包括在风险调整模型，并计算年度百分比变化（APC）的趋势，使用联合点回归。我们评估了婴儿20年的存活率，
Objective To analyse survival trends and regional variation for very preterm infants admitted to neonatal care.Setting All neonatal units in England.Patients Infants born at 22(+0)-31(+6) weeks(+days)gestational age (GA) over 2008-2014 and admitted to neonatal care; published data for admitted infants 22(+0)-25(+6) weeks(+days) GA in 1995 and 2006, and for live births at 22(+0)-31(+6) weeks(+days) GA in 2013.Methods We obtained data from the National Neonatal Research Database. We used logistic regression to model survival probability with birth weight, GA, sex, antenatal steroid exposure and multiple birth included in the risk adjustment model and calculated annualpercentage change (APC) for trends using joinpoint regression. We evaluated survival over a 20-year period for infants