A Guide to the Perplexed on the Specificity of Antibodies
A Guide to the Perplexed on the Specificity of Antibodies
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DOI：
10.1369/jhc.2008.952770
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发表时间：
2009-01-01
影响因子：
3.2
通讯作者：
Saper, Clifford B.
中科院分区：
文献类型：
--
作者：
Saper, Clifford B.
许多研究人员不知道抗体特异性的潜在问题，也不知道需要为所使用的每种抗体仔细记录抗体表征。在这篇综述中，我考虑抗体作用的原则，以及它们如何定义一组规则，即在严肃的科学调查中使用抗体之前，调查者应该获得哪些信息。（J Histochem Cytochem 57：1-5，2009）
Many investigators are unaware of the potential problems with specificity of antibodies and the need to document antibody characterization meticulously for each antibody that is used. In this review, I consider the principles of antibody action and how they define a set of rules for what information should be obtained by the investigator before using an antibody in a serious scientific investigation. (J Histochem Cytochem 57:1-5, 2009)