PARTICLE-SIZE OF WHEAT, MAIZE, AND OAT TEST MEALS - EFFECTS ON PLASMA-GLUCOSE AND INSULIN RESPONSES AND ON THE RATE OF STARCH DIGESTION INVITRO
PARTICLE-SIZE OF WHEAT, MAIZE, AND OAT TEST MEALS - EFFECTS ON PLASMA-GLUCOSE AND INSULIN RESPONSES AND ON THE RATE OF STARCH DIGESTION INVITRO
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DOI：
10.1093/ajcn/47.4.675
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发表时间：
1988-04-01
影响因子：
7.1
通讯作者：
BOLTON, CH
中科院分区：
文献类型：
--
作者：
HEATON, KW;MARCUS, SN;BOLTON, CH
当正常志愿者食用等热量的小麦餐时，他们的血浆胰岛素反应（峰值浓度和曲线下面积）逐步增加：全谷物<碎谷物<粗面粉<细面粉。使用细玉米粒的胰岛素反应也比使用完整或破碎的玉米粒的胰岛素反应更大，但与完整的去壳谷物、燕麦片和细燕麦片相似。小麦粉的血糖峰值到最低值的波动大于碎粒或全粒谷物。在体外淀粉水解胰淀粉酶是更快的颗粒大小与所有三种谷物。与体内数据的相关性不完善。以燕麦为基础的膳食比以小麦或玉米为基础的膳食引起更小的葡萄糖和胰岛素反应。颗粒大小影响小麦和玉米的消化率和随后的代谢效应，但不影响燕麦。对细磨面粉的胰岛素反应增加可能与高胰岛素血症相关疾病的病因和糖尿病的管理有关。
When normal volunteers ate isocaloric wheat-based meals, their plasma insulin responses (peak concentration and area under curve) increased stepwise: whole grains < cracked grains < coarse flour < fine flour. Insulin responses were also greater with fine maizemeal than with whole or cracked maize grains but were similar with whole groats, rolled oats, and fine oatmeal. The peak-to-nadir swing of plasma glucose was greater with wheat flour than with cracked or whole grains. In vitro starch hydrolysis by pancreatic amylase was faster with decreasing particle size with all three cereals. Correlation with the in vivo data was imperfect. Oat-based meals evoked smaller glucose and insulin responses than wheat-or maize-based meals. Particle size influences the digestion rate and consequent metabolic effects of wheat and maize but not oats. The increased insulin response to finely ground flour may be relevant to the etiology of diseases associated with hyperinsulinemia and to the management of diabetes.