Clinical and Resistance Consequences of Misquantification of Plasma and Cerebrospinal Fluid Human Immunodeficiency Virus Type 1 (HIV-1) RNA in Samples from an HIV-1 Subtype G-Infected Patient
Clinical and Resistance Consequences of Misquantification of Plasma and Cerebrospinal Fluid Human Immunodeficiency Virus Type 1 (HIV-1) RNA in Samples from an HIV-1 Subtype G-Infected Patient
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DOI：
10.1128/jcm.00206-09
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发表时间：
2009-11-01
影响因子：
9.4
通讯作者：
Simon, Francois
中科院分区：
文献类型：
--
作者：
Delaugerre, Constance;Denis, Blandine;Simon, Francois
人类免疫缺陷病毒(HIV)载量是监测抗病毒治疗效果和耐药性的主要标志。我们报告了一例HIV-1 G亚型感染妇女血浆和脑脊液中HIV-1(HIV-1)RNA定量不足的病例，导致HIV脑炎延迟诊断和出现耐药性。
Human immunodeficiency virus (HIV) load is the main marker used to monitor antiviral treatment efficacy and resistance. We report a case of underquantification of HIV type 1 (HIV-1) RNA in plasma and cerebrospinal fluid from an HIV-1 subtype G-infected woman, leading to delayed diagnosis of HIV encephalitis and to the emergence of drug resistance.