Forced- and Self-Rotation of Magnetic Nanorods Assembly at the Cell Membrane: A Biomagnetic Torsion Pendulum
Forced- and Self-Rotation of Magnetic Nanorods Assembly at the Cell Membrane: A Biomagnetic Torsion Pendulum
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DOI：
10.1002/smll.201701274
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发表时间：
2017-08-18
期刊：
影响因子：
13.3
通讯作者：
Wilhelm, Claire
中科院分区：
文献类型：
--
作者：
Mazuel, Francois;Mathieu, Samuel;Wilhelm, Claire
为了深入了解各向异性纳米物体如何与活细胞膜相互作用以及可能的自组装，通过在磁场下在聚合物基质内组装氧化铁纳米立方体来设计平均尺寸约为 100 nm x 1 μm 的磁性纳米棒。然后探索旋转磁场影响下细胞膜上的纳米生物界面。观察到与膜交织的纳米棒的复杂结构。出乎意料的是，在磁旋转刺激后，产生的大棒能够自由旋转多次，揭示了生物磁扭摆的产生。
In order to provide insight into how anisotropic nano-objects interact with living cell membranes, and possibly self-assemble, magnetic nanorods with an average size of around 100 nm x 1 mu m are designed by assembling iron oxide nanocubes within a polymeric matrix under a magnetic field. The nano-bio interface at the cell membrane under the influence of a rotating magnetic field is then explored. A complex structuration of the nanorods intertwined with the membranes is observed. Unexpectedly, after a magnetic rotating stimulation, the resulting macrorods are able to rotate freely for multiple rotations, revealing the creation of a biomagnetic torsion pendulum.