The development of an autonomous self-powered bio-sensing actuator
The development of an autonomous self-powered bio-sensing actuator
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DOI：
10.1016/j.snb.2014.01.117
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发表时间：
2014-06-01
影响因子：
8.4
通讯作者：
Sode, Koji
中科院分区：
文献类型：
--
作者：
Hanashi, Takuya;Yamazaki, Tomohiko;Sode, Koji
生物燃料电池固有的低功率供应限制了它们作为可植入设备电源的应用。为了克服这些限制，我们先前开发了一种称为“生物电容器”的新型设备（Hanashi等人，2009年）。生物电容产生足够稳定的电力来运行生物传感装置和信号传感器。在本文中，我们报告了一种自主，自供电，传感执行器，采用生物电容器的原理为核心技术。该装置由生物电容器组成，生物电容器采用直接电子转移型葡萄糖酶燃料电池，连接步进电机作为致动器。在葡萄糖存在的情况下，生物电容器能够产生足够的电力来操作执行器。步进电机的转矩和转速取决于BioCapacitor中使用的电容器的电容和葡萄糖浓度。较高的葡萄糖浓度为步进电机提供较高的扭矩和速度，这是由于电容器的充放电频率作为阳极酶反应的函数而产生的。该驱动器完全由葡萄糖氧化产生的能量驱动，其性能受葡萄糖浓度的调节。我们还展示了采用自主、自供电、传感执行器的液体泵送系统的性能，这表明了其作为药物输送/泵送系统的应用潜力。(C) 2014 Elsevier B.V.版权所有
The inherent low power supplies from biofuel cells limits their application as power sources in implantable devices. To overcome these limitations, we have previously developed a novel device designated as a "BioCapacitor" (Hanashi et al., 2009). The BioCapacitor generates sufficient stable power to operate biosensing devices and signal transducers. In this paper, we report an autonomous, self-powered, sensing actuator that employs the principle of BioCapacitor as the core technology. The device is composed of a BioCapacitor, which uses a direct electron transfer-type glucose enzyme fuel cell, connected to a stepper motor as the actuator. In the presence of glucose, the BioCapacitor was able to generate enough electricity to operate the actuator. The torque and rotational speed of the stepper motor was dependent on the capacitance of the capacitor used in the BioCapacitor, and on the glucose concentration. A higher glucose concentration provided the stepper motor with higher torque and speed, resulting from the charge/discharge frequency of the capacitor as a function of the enzyme reaction at the anode. The actuator was operated entirely by the energy derived from glucose oxidation, and its performance was regulated by the glucose concentration. We also present the performance of a liquid-pumping system that employs the autonomous, self-powered, sensing actuator, which demonstrates its potential for application as a drug delivery/pumping system. (C) 2014 Elsevier B.V. All rights reserved.