Sequential isomerization and ring-closing metathesis: masked styryl and vinyloxyaryl groups for the synthesis of benzo-fused heterocycles
Sequential isomerization and ring-closing metathesis: masked styryl and vinyloxyaryl groups for the synthesis of benzo-fused heterocycles
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DOI：
10.1016/s0040-4039(03)01545-4
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发表时间：
2003-08-18
影响因子：
1.8
通讯作者：
de Koning, CB
中科院分区：
文献类型：
--
作者：
van Otterlo, WAL;Ngidi, EL;de Koning, CB
使用芳基烯丙基醚和芳基烯丙基作为掩蔽的乙烯基醚和I-丙烯基苯基用于闭环复分解（RCM），导致合成苯并稠合的杂环，这通过使用氯离子介导的异构化，然后通过氯离子介导的RCM反应来证明。这导致了多种产物的合成，包括两个取代的苯并[1，4]二恶英，萘并[2，3-B][1，4]二恶英，2 H-色烯和苯并[B]呋喃。(C)2003 Elsevier Ltd.保留所有权利。
The use of an aryl allyl ether and an arylallyl group as masked vinyl ether and I-propenylphenyl groups for ring-closing metathesis (RCM) leading to the synthesis of benzo-fused heterocycles was demonstrated by using a ruthenium-mediated isomerization followed by a ruthenium-mediated RCM reaction. This resulted in the syntheses of a variety of products including two substituted benzo[1,4]dioxins, a naphtho[2,3-b][1,4]dioxin, a 2H-chromene and a benzo[b]furan. (C) 2003 Elsevier Ltd. All rights reserved.