Pulse pressure and heart rate: Independent risk factors for cancer?
Pulse pressure and heart rate: Independent risk factors for cancer?
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DOI：
10.1016/s0895-4356(00)00353-x
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发表时间：
2001-07-01
影响因子：
7.2
通讯作者：
Benetos, A
中科院分区：
文献类型：
--
作者：
Thomas, F;Guize, L;Benetos, A
在本研究中，心率（HR）和脉压（PP）对癌症死亡率的作用，考虑到体力活动，吸烟，饮酒和其他混杂因素或基础疾病，在男性中进行了检查。该研究包括125，513名年龄在20至95岁之间的男性，他们在1978年至1988年期间在IPC中心进行了健康检查。HR和PP分为三组：< 60，60-80。心率> 80 bpm，< 50 bpm。51-64. PP大于或等于65 mmHg。所有癌症死亡率从一个HR或PP类别到下一个类别的增量相关的校正风险比分别为1.4（1.2-1.5）和1.3（1.1-1.4）。这种关系独立于几个已知的风险和混杂因素，特别是吸烟和体力活动。并且不能用潜在疾病的存在来解释。(C)2001年，Elsevier Science Inc. All rights reserved.
In the present study, the roles of heart rate (HR) and pulse pressure (PP) on cancer mortality, after taking into account physical activity, cigarette smoking, alcohol consumption and other confounding factors or underlying disease, were examined in men. The study included 125,513 men aged 20 to 95 years who had a health check-up at the IPC Center between 1978 and 1988. HR and PP were classified into three groups: < 60, 60-80. > 80 bpm for HR and < 50. 51-64. greater than or equal to 65 mmHg for PP. Adjusted risk ratios related to the increment from one class of HR or PP to the next for all cancer mortality were 1.4 (1.2-1.5) and 1.3 (1.1-1.4), respectively. This relationship was independent of several known risk and confounding factors, especially cigarette smoking and physical activity. and could not be explained by the presence of underlying disease. (C) 2001, Elsevier Science Inc. All rights reserved.