Unexpected Electron Transfer in Cryptochrome Identified by Time-Resolved EPR Spectroscopy
Unexpected Electron Transfer in Cryptochrome Identified by Time-Resolved EPR Spectroscopy
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DOI：
10.1002/anie.201104321
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发表时间：
2011-01-01
影响因子：
16.6
通讯作者：
Weber, Stefan
中科院分区：
文献类型：
--
作者：
Biskup, Till;Hitomi, Kenichi;Weber, Stefan
调节光诱导电子转移：尽管氧化还原伴侣的结构高度保守，但局部序列和构象的细微差异可以产生蛋白质中电子转移（ET）的多样性和特异性。对于单个ET步骤，距离不一定是决定性参数；ET的取向和溶剂可及性，因此，电荷分离态的稳定起着重要的作用。
Tuning photoinduced electron transfer: Subtle differences in local sequence and conformation can produce diversity and specificity in electron transfer (ET) in proteins, despite high structural conservation of redox partners. For individual ET steps, distance is not necessarily the decisive parameter; orientation and solvent accessibility of ET partners, and therefore, stabilization of charge-separated states contribute substantially.