Fusion peptide from SARS-2 spike transforms into a wedge inserted in a bilayer leaflet, and thins the opposite leaflet
Fusion peptide from SARS-2 spike transforms into a wedge inserted in a bilayer leaflet, and thins the opposite leaflet
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DOI：
10.1016/j.bpj.2021.11.2343
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发表时间：
2022-02-11
影响因子：
3.4
通讯作者：
Koppisetti RK
中科院分区：
文献类型：
--
作者：
Doren SR;Scott B;Fulcher YG;Koppisetti RK
SNARE 组装，但它们不足以进行膜融合。相反，脂质 PE、PA、PS 和 DAG 各自促进膜融合最后步骤的双层重排。因此，受调节的膜融合需要多组脂质用于融合途径中的不同步骤。
SNARE assembly, but they are not sufficient for membrane fusion. Rather, the lipids PE, PA, PS, and DAG each promote bilayer rearrangement for the final step of membrane fusion. Thus, regulated membrane fusion requires multiple sets of lipids for different steps in the fusion pathway.