Enhancement of magnetization transfer effects by inter-molecular multiple quantum filtered NMR
Enhancement of magnetization transfer effects by inter-molecular multiple quantum filtered NMR
复制标题
DOI：
10.1016/j.jmr.2007.09.017
复制
发表时间：
2008-01-01
影响因子：
2.2
通讯作者：
Navon, Gil
中科院分区：
文献类型：
--
作者：
Eliav, Uzi;Navon, Gil
有许多方法可以基于由于磁化转移到大分子而导致的水的M-z磁化的变化来提供MRI对比度。在目前的工作中，我们报告了将这些方法与分子间多量子相干(IMQC)相结合可以得到增强的效果。对于磁化传递对比法，(M-z/M-0)的影响变为(M-z/M-0)(L)，其中L是构成磁化传递对比的张量的阶。将iMQC与高盛-沈南鹏的实验结合起来，也发现了类似的趋势。指出该方法对包括核Overhaser效应在内的所有磁化传递方法都是通用的。(C)2007 Elsevier Inc.保留所有权利。
There are a number of methods that give MRI contrasts based on changes of the water M-z magnetization as a result of magnetization transfer to macromolecules. In the present work we report that a combination of these methods with inter-molecular multiple quantum coherences (iMQC) gives enhanced effects. For the magnetization transfer contrast (MTC) method an effect of (M-z/M-0) becomes (M-z/M-0)(l) where l is the rank of the tensors constituting the iMQC. A similar trend was found upon combining iMQC with the Goldman - Shen experiment. It is pointed out that the method is general for all magnetization transfer methods, including the nuclear Overhauser effect. (c) 2007 Elsevier Inc. All rights reserved.