The risk of stroke in spouses of people living with dementia in Korea
The risk of stroke in spouses of people living with dementia in Korea
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DOI：
10.1177/1747493016677987
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发表时间：
2017-10-01
影响因子：
6.7
通讯作者：
Simpson, Annie N.
中科院分区：
文献类型：
--
作者：
Hong, Ickpyo;Han, Areum;Simpson, Annie N.
背景和目的随着韩国人口老龄化，痴呆症患者数量预计将会增加。尽管之前的研究报告称，与护理相关的负担会影响痴呆症患者配偶的健康，但尚不清楚这些配偶是否会增加中风的风险。我们研究了痴呆症患者 (SPD) 的配偶中风风险之间的关系。 方法 我们从 2012 年和 2013 年韩国社区健康调查的人口调查中总共检索了 314,526 名受访者。我们使用未匹配和匹配样本（1:1 贪婪匹配），使用逻辑回归模型检查 SPD 的中风风险。结果 2012 年和 2013 年，共有 3868 名配偶（占韩国人口的 1.2%）与痴呆症患者同住。在我们对与痴呆症患者同住的人和非痴呆症患者的样本进行匹配后，所有基线人口统计数据均平衡（p>0.05），包括性别、年龄、收入、教育、保险、吸烟、饮酒、压力水平。在控制了中风危险因素（包括人口统计学和九种慢性病）后，与痴呆症患者同住的配偶比与非痴呆症配偶同住的配偶在未匹配样本（调整后优势比（AOR），1.70；95%CI，1.47-1.96）和匹配样本（AOR，1.69；95%CI，1.35-2.10）中患中风的风险更高。结论 在匹配的样本中，与痴呆症患者一起生活与中风的几率增加 69% 相关。应密切监测痴呆症患者的配偶，并就中风的危险因素进行教育。
Background and purpose As the Korean population ages, the number of patients with dementia is expected to increase. Although prior studies have reported that the burdens associated with caregiving impact the health of spouses of individuals with dementia, it is unclear whether those spouses have increased risk of stroke. We examined the relationship between the risks of stroke among spouses of people with dementia (SPD).Methods We retrieved a total of 314,526 respondents from the population-based surveys of the 2012 and 2013 Korea Community Health Survey. We used unmatched and matched samples (1:1 Greedy matching) to examine the risk of stroke for SPD using logistic regression models.Results A total of 3868 spouses (1.2% of the Korean population) lived with a patient with dementia in 2012 and 2013. After we matched samples of those who live with a patient with dementia and those who do not, all baseline demographics were balanced (p>0.05), including sex, age, income, education, insurance, smoking, drinking, stress level. The spouses who lived with a patient with dementia had a higher risk of stroke than those who lived with non-dementia spouse in both the unmatched (adjusted odds ratios (AOR), 1.70; 95%CI, 1.47-1.96) and matched samples (AOR, 1.69; 95%CI, 1.35-2.10) after controlling for stroke risk factors, including demographics and nine chronic conditions.Conclusions Living with a patient with dementia is associated with a 69% increased odds of stroke in the matched sample. Spouses of individuals with dementia should be closely monitored and educated for risk factors of stroke.