Palladimn(II)-catalyzed one-pot enantioselective synthesis of arylglycine derivatives from ethyl glyoxylate, p-toluenesulfonyl isocyanate and arylboronic acids
Palladimn(II)-catalyzed one-pot enantioselective synthesis of arylglycine derivatives from ethyl glyoxylate, p-toluenesulfonyl isocyanate and arylboronic acids
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DOI：
10.1002/adsc.200700362
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发表时间：
2008-01-01
影响因子：
5.4
通讯作者：
Lu, Xiyan
中科院分区：
文献类型：
--
作者：
Dai, Huixiong;Yang, Miao;Lu, Xiyan
以乙二酸乙酯、对甲苯磺酰基异氰酸酯和芳基硼酸为原料，钯(II)催化，一锅法对映体选择性地合成了芳基甘氨酸衍生物，产率和对映选择性均较好。该反应为芳基甘氨酸的合成提供了一种简便有效的方法。
A palladium (II)-catalyzed, one-pot enantioselective synthesis of arylglycine derivatives from ethyl glyoxylate, p-toluenesulfonyl isocyanate and arylboronic acids giving moderate to good yields and enantioselectivity has been developed. This reaction provides a convenient and efficient method for the synthesis of arylglycines.