Vertebrate evolution: doubling and shuffling with a full deck.
Vertebrate evolution: doubling and shuffling with a full deck.
复制标题
脊椎动物进化：用整副牌进行加倍和洗牌。
DOI：
10.1016/s0168-9525(02)00008-2
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发表时间：
2003
期刊：
影响因子：
--
通讯作者：
Durand,Dannie
中科院分区：
文献类型：
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作者：
Durand,Dannie
The number and role of whole-genome duplications in vertebrate evolution has intrigued evolutionary biologists since Ohno first proposed genome duplication as the force driving the ‘big leap' in vertebrate morphological innovation. Attempts to resolve these issues have been thwarted by small and noisy datasets, and by lack of computational accuracy and statistical rigor. Recently, Ken Wolfe and colleagues presented a genome-scale, statistically rigorous analysis of evidence based on the spatial organization of duplicated genes, as well as estimates of duplication times. Their results provide the strongest evidence to date of large-scale duplication throughout the vertebrate genome, consistent with at least one whole-genome duplication.
