Molecularly imprinted nanocomposites for highly sensitive SPR detection of a non-aqueous atrazine sample
Molecularly imprinted nanocomposites for highly sensitive SPR detection of a non-aqueous atrazine sample
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DOI：
10.1039/b803350a
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发表时间：
2009-01-01
期刊：
影响因子：
4.2
通讯作者：
Sugimoto, Naoki
中科院分区：
文献类型：
--
作者：
Matsui, Jun;Takayose, Megumi;Sugimoto, Naoki
以金薄膜为传感器芯片，将金纳米粒子固定在莠去津分子印迹聚合物上，制备了一种对除草剂莠去津具有高灵敏度和高选择性的表面等离子体共振（SPR）传感器。在检测中，阿特拉津印迹聚合物有望作为人工合成受体，在有机溶剂中选择性捕获阿特拉津，而金纳米颗粒有望与金薄膜产生耦合效应，增强纳米颗粒与金薄膜之间的局部电磁场，使传感器芯片对微环境极性变化具有高度敏感性。因此，阿特拉津印迹聚合物和金纳米颗粒的组合使我们能够组成SPR传感器，证明在乙腈中检测5 pM阿特拉津。
A surface plasmon resonance (SPR) sensor highly sensitive and selective for the herbicide atrazine was composed by immobilizing atrazine-imprinted polymer with gold nanoparticles on a gold thin film as a sensor chip. In the detection, the atrazine-imprinted polymer was expected to work as synthetic receptor for selectively capturing atrazine in organic solvent, and the gold nanoparticles were expected to exhibit a coupling effect with the gold thin film to enhance the local electromagnetic field between the nanoparticles and the gold film, making the sensor chip highly sensitive for changes in microenvironmental polarity. Thus, a combination of the atrazine-imprinted polymer and gold nanoparticles enabled us to compose an SPR sensor demonstrating the detection of 5 pM atrazine in acetonitrile.