Dissecting desaturation: Plants prove advantageous
Dissecting desaturation: Plants prove advantageous
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DOI：
10.1016/0962-8924(96)10002-7
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发表时间：
1996-04-01
影响因子：
19
通讯作者：
Browse, J
中科院分区：
文献类型：
--
作者：
Somerville, C;Browse, J
脂肪酸脱饱和酶在控制膜的物理性质和合成前列腺素和信息素等信号分子方面发挥着重要作用。大多数去饱和酶是膜蛋白，不能用传统的生物化学方法进行表征。这类酶只有一种是从动物或真菌中鉴定出来的。在这种情况下，植物已被证明是有用的实验材料来源。在表征和操纵九类控制植物膜和植物储存脂的脂肪酸组成的去饱和酶方面已经取得了实质性的进展，这些脂肪约占人类饮食中热量的30%。
Fatty acid desaturases play important roles in controlling the physical properties of membranes and in the synthesis of signal molecules such as prostaglandins and pheromones. Most desaturases are membrane proteins that have been recalcitrant to characterization by conventional biochemical methods. Only one enzyme of this class has been characterized from animals or fungi.In this context, plants have proved to be useful sources of experimental materials. Substantial progress has been made in characterizing and manipulating nine classes of desaturases that control the fatty acid composition of both plant membranes and plant storage lipids, which account for similar to 30% of the calories in the human diet.