Proton transport and cell function.
Proton transport and cell function.
复制标题
质子运输和细胞功能。
DOI：
10.1172/jci111212
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发表时间：
1984
期刊：
影响因子：
--
通讯作者：
RectorJr,FC
中科院分区：
文献类型：
--
作者：
Ives,HE;RectorJr,FC
在过去的五年中，关于H+转运在细胞功能中的许多不同作用的信息爆炸式增长。H+转运涉及细胞功能的三个广泛领域：(a)维持和改变细胞内pH以启动特定的细胞事件，(b)在细胞局部区域产生pH梯度，包括涉及能量转导的梯度，以及(c)上皮离子转运。这些过程都涉及一种或多种氢离子转运机制。本综述的第一部分将讨论这些H+转运机制，第二部分将讨论由H+转运控制的细胞功能。
The past five years have witnessed an explosion of information on the many and varied roles of H+ transport in cell function. H+ transport is involved in three broad areas of cell function: (a) maintenance and alteration of intracellular pH for initiation of specific cellular events, (b) generation of pH gradients in localized regions of the cell, including gradients involved in energy transduction, and (c) transepithelial ion transport. These processes each involve one or more of several H+ translocating mechanisms. The first section of this review will discuss these H+ translocating mechanisms and the second part will deal with the cellular functions controlled by H+ transport.