The estimation of the genetic correlation: the use of the jackknife
The estimation of the genetic correlation: the use of the jackknife
复制标题
遗传相关性的估计：使用折刀
DOI：
10.1038/hdy.1994.153
复制
发表时间：
1994
期刊：
影响因子：
3.8
通讯作者：
R. Preziosi
中科院分区：
文献类型：
--
作者：
D. Roff;R. Preziosi
为了充分理解数量性状的进化过程，有必要能够估计遗传相关及其相关的标准误差。目前，估计方法仅适用于相对简单的设计。另一种方法是使用家庭平均值的相关性作为遗传相关性的估计。我们评估的效用的家庭平均值的方法和更一般的程序，刀切。除非家庭规模非常大（≈ 20），否则家庭平均值方法可能非常有偏差，因此其通用性值得怀疑。然而，折刀法确实提供了相关性（表型和遗传）及其标准误差的有效估计。
To understand fully the process of evolution of quantitative traits it is necessary to be able to estimate the genetic correlation and its associated standard error. At present, estimation methods are available only for relatively simple designs. An alternative procedure is to use the correlation of family means as an estimate of the genetic correlation. We evaluate the utility of the family mean method and that of the more general procedure, the jackknife. The family mean method is shown to be potentially very biased unless family sizes are very large (≈ 20), and therefore its general utility is questionable. However, the jackknife method does provide valid estimates of both the correlations (phenotypic and genetic) and their standard errors.