Recreational exposure to aerosolized brevetoxins during Florida red tide events

Recreational exposure to aerosolized brevetoxins during Florida red tide events
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DOI:
10.1016/s1568-9883(03)00005-2
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发表时间:
2003-03-01
期刊:
影响因子:
6.6
通讯作者:
Baden, DG
Baden, DG
中科院分区:
生物学2区
文献类型:
--
作者:
Backer, LC;Fleming, LE;Baden, DG

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在两次独立的Karenia brevis赤潮事件中,我们测量了空气和水样中的短尾藻毒素水平,进行了个人访谈,并在人们访问佛罗里达两个海滩之一之前和之后对他们进行了肺功能测试。我们在美国佛罗里达州萨拉索塔和杰克逊维尔发生赤潮期间进行了这项研究,共有129人参加。暴露分为三个级别:低/无暴露、中等暴露和高暴露。8%的未接触者、11%的中度接触者和28%的高度接触者报告了下呼吸道症状(如喘息)。我们对中度或高度接触的人进行了鼻咽拭子检查,发现超过33%的参与者出现了炎症反应。我们没有发现肺功能检查结果的任何临床显著变化;然而,研究人群很小。在未来的流行病学研究中,我们计划进一步调查吸入短尾寒螺毒素对人类健康的影响。出版社:Elsevier Science B. V.
During two separate Karenia brevis red tide events, we measured the levels of brevetoxins in air and water samples, conducted personal interviews, and performed pulmonary function tests on people before and after they visited one of two Florida beaches. One hundred and twenty-nine people participated in the study, which we conducted during red tide events in Sarasota and Jacksonville, FL, USA. Exposure was categorized into three levels: low/no exposure, moderate exposure, and high exposure. Lower respiratory symptoms (e.g. wheezing) were reported by 8% of unexposed people, 11% of the moderately exposed people, and 28% of the highly exposed people. We performed nasal-pharyngeal swabs on people who experienced moderate or high exposure, and we found an inflammatory response in over 33% of these participants. We did not find any clinically significant changes in pulmonary function test results; however, the study population was small. In future epidemiologic studies, we plan to further investigate the human health impact of inhaled brevetoxins. Published by Elsevier Science B.V.