Assessment of magnetic resonance techniques to measure muscle damage 24 h after eccentric exercise
Assessment of magnetic resonance techniques to measure muscle damage 24 h after eccentric exercise
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DOI：
10.1111/sms.12234
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发表时间：
2015-02-01
影响因子：
4.1
通讯作者：
Davies, R. C.
中科院分区：
文献类型：
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作者：
Fulford, J.;Eston, R. G.;Davies, R. C.
该研究检查了许多不同的磁共振（MR）方法中的哪一种对检测离心运动引起的肌肉损伤敏感。17名健康，身体活跃的参与者，肌肉损伤证实非MR方法进行离心运动后24小时进行测试。技术调查是否可以检测到损伤的四头肌作为一个整体，并单独在股直肌，股外侧肌（VL），股内侧肌（VM），股中间肌（VI）。相对于基线值，腿部和肌肉横截面积和体积以及静息无机磷酸盐浓度发生了显著变化。所有肌肉的横向弛豫时间（T2）和表观扩散系数（ADC）值也出现了显著的时间效应，T2的VL、VM和VI以及ADC的VI出现了单独的显著变化。肌肉体积与平均T2变化之间存在显著相关性（r=0.59），但T2与ADC或Pi变化之间不存在显著相关性。对于基线pH值、磷酸肌酸（PCr）、磷酸二酯或ATP代谢物浓度或描述运动后PCr恢复率的时间常数，所有肌肉的磁化传递对比图像均无显著时间效应。
The study examined which of a number of different magnetic resonance (MR) methods were sensitive to detecting muscle damage induced by eccentric exercise. Seventeen healthy, physically active participants, with muscle damage confirmed by non-MR methods were tested 24h after performing eccentric exercise. Techniques investigated whether damage could be detected within the quadriceps muscle as a whole, and individually within the rectus femoris, vastus lateralis (VL), vastus medialis (VM), and vastus intermedius (VI). Relative to baseline values, significant changes were seen in leg and muscle cross-sectional areas and volumes and the resting inorganic phosphate concentration. Significant time effects over all muscles were also seen in the transverse relaxation time (T2) and apparent diffusion coefficient (ADC) values, with individually significant changes seen in the VL, VM, and VI for T2 and in the VI for ADC. A significant correlation was found between muscle volume and the average T2 change (r=0.59) but not between T2 and ADC or Pi alterations. There were no significant time effects over all muscles for magnetization transfer contrast images, for baseline pH, phosphocreatine (PCr), phosphodiester, or ATP metabolite concentrations or the time constant describing the rate of PCr recovery following exercise.