Using 80 kVp versus 120 kVp in perfusion CT measurement of regional cerebral blood flow.
Using 80 kVp versus 120 kVp in perfusion CT measurement of regional cerebral blood flow.
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发表时间：
2000-11
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通讯作者：
Max Wintermark;Philippe Maeder;F. Verdun;Jean-Philippe Thiran;J. Valley;Pierre Schnyder;R. Meuli
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作者：
Max Wintermark;Philippe Maeder;F. Verdun;Jean-Philippe Thiran;J. Valley;Pierre Schnyder;R. Meuli
局部脑血流量(RCBF)的CT灌注研究，包括在静脉注射造影剂期间对大脑CT切片的顺序采集，经典的报道是在120kVp下实现的。我们假设使用80kVp应该会产生相同的图像质量，同时显著降低患者的辐射剂量，我们对这一假设进行了评估。在5例接受头颅CT检查的患者中，在静脉注射含碘造影剂前后，分别在120kVp和80kVp下对其中一个层面进行成像。对每个患者的这四个大脑CT切片进行了对比、噪声和辐射剂量的分析。80kVp时的对比度增强显著(P<；.001)，对比度增强后灰质和白质之间的对比度也显著增加(P<；.001)。80kVp时的平均噪声差异无统计学意义(P=0.042)。最后，在80kVp下进行CT灌注研究，保持mAs恒定，可将辐射剂量降低2.8倍。因此，我们得出结论，在减少患者照射的情况下，80kVp的rCBF灌注CT研究将导致对比度增强，并应改善rCBF分析。
Perfusion CT studies of regional cerebral blood flow (rCBF), involving sequential acquisition of cerebral CT sections during IV contrast material administration, have classically been reported to be achieved at 120 kVp. We hypothesized that using 80 kVp should result in the same image quality while significantly lowering the patient's radiation dose, and we evaluated this assumption. In five patients undergoing cerebral CT survey, one section level was imaged at 120 kVp and 80 kVp, before and after IV administration of iodinated contrast material. These four cerebral CT sections obtained in each patient were analyzed with special interest to contrast, noise, and radiation dose. Contrast enhancement at 80 kVp is significantly increased (P < .001), as well as contrast between gray matter and white matter after contrast enhancement (P < .001). Mean noise at 80 kVp is not statistically different (P = .042). Finally, performance of perfusion CT studies at 80 kVp, keeping mAs constant, lowers the radiation dose by a factor of 2.8. We, thus, conclude that 80 kVp acquisition of perfusion CT studies of rCBF will result in increased contrast enhancement and should improve rCBF analysis, with a reduced patient's irradiation.