Detecting cross talk between two halves of a phospholipid bilayer.
Detecting cross talk between two halves of a phospholipid bilayer.
复制标题
检测磷脂双层两半之间的串扰。
DOI：
10.1021/la701503v
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发表时间：
2007
期刊：
影响因子：
--
通讯作者：
Regen,StevenL
中科院分区：
文献类型：
--
作者：
Zhang,Jianbing;Jing,Bingwen;Janout,Vaclav;Regen,StevenL
与生物膜的结构和功能有关的最具挑战性的问题之一是双层的两半是否相互“交谈”。在这封信中，我们展示了液体磷脂双分子层的一个小叶的横向组织如何被外部因子扰动，也改变了相邻小叶的横向组织。此外，我们表明，这种“串扰”所涉及的能量相当于约100 cal/mol的磷脂。这些发现为期望类似的串音存在于细胞膜中提供了基础。
One of the most challenging questions that relates to the structure and function of biological membranes is whether the two halves of the bilayer “talk” to each other. In this letter, we show how the pertubation of the lateral organization of one leaflet of a fluid phospholipid bilayer by an external agent also alters the lateral organization of the adjoining leaflet. In addition, we show that the energy involved in such “cross talk” corresponds to ca. 100 cal/mol of phospholipid. These findings provide a basis for expecting similar cross talk to exist in cell membranes.