The first reported case of intestinal spirochaetosis in Japan
The first reported case of intestinal spirochaetosis in Japan
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日本首例肠道螺旋体病报告
DOI：
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发表时间：
1998
期刊：
影响因子：
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通讯作者：
S. Sasou
中科院分区：
文献类型：
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作者：
Shinro Nakamura;T. Kuroda;T. Sugai;S. Ono;Toru Yoshida;I. Akasaka;Fumie Nakashima;S. Sasou
一名65岁的日本男性于1994年1月19日到日本小津县医院就诊，抱怨体重减轻。盲肠粘膜活检材料经苏木素-伊红染色显示，覆盖表面上皮的厚的，嗜碱性模糊条纹。透射电镜和扫描电镜观察显示，存在端部变细的微波浪状螺旋体，通过其中一端附着在结肠黏膜表面上皮上。患者没有表现出任何炎症性肠病的临床症状，实验室检查消除了免疫缺陷状况。因此，在本例中，肠道螺旋体似乎是无害的共栖生物。本文报道了日本第一例肠螺旋体病。
A 65‐year‐old Japanese male consulted Ozuchi Prefectural Hospital (Iwate, Japan) on 19 January 1994 complaining of weight loss. Cecal mucosal biopsy material, which was stained with hematoxylln‐eosin revealed a thick, basophllic fuzzy fringe covering the surface epithelium. Transmission and scanning electron microscopy observations demonstrated the presence of slightly wavy spirochaetes with tapered ends, which were attached to the surface epithelium of the colonlc mucosa via one of these ends. The patient did not display any clinical symptoms of Inflammatory bowel disease, and laboratory tests eliminated an Immunodeficiency condition. Thus, in the present case, the Intestinal spirochaetes appear to be harmless commensals. This paper presents the first reported case of Intestinal spirochaetosis fn Japan.