Neural bases of learning and memory: Functional neuroimaging evidence

Neural bases of learning and memory: Functional neuroimaging evidence
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DOI:
10.1097/00019052-200008000-00008
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发表时间:
2000-08-01
影响因子:
4.8
通讯作者:
Nyberg, Lars
Nyberg, Lars
中科院分区:
医学2区
文献类型:
--
作者:
Cabeza, Roberto;Nyberg, Lars

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正电子发射断层扫描和功能磁共振成像研究已经确定了与不同形式的记忆相关的大脑区域。工作记忆主要与双侧前额叶和顶叶区域有关。左前额叶和颞叶区域的语义记忆;左前额叶和内侧颞区的情景记忆编码;右前额叶、后中线和内侧颞区的情景记忆检索;以及运动、顶叶和皮质下区域的技能学习。最近的研究通过分离复杂记忆任务的不同子成分的神经相关性以及较大大脑区域的不同子区域的认知作用,提供了更高的特异性。
Positron emission tomography and functional magnetic resonance imaging studies have identified brain regions associated with different forms of memory. Working memory has been associated primarily with the bilateral prefrontal and parietal regions; semantic memory with the left prefrontal and temporal regions; episodic memory encoding with the left prefrontal and medial temporal regions; episodic memory retrieval with the right prefrontal, posterior midline and medial temporal regions; and skill learning with the motor, parietal, and subcortical regions. Recent studies have provided higher specificity, by dissociating the neural correlates of different subcomponents of complex memory tasks, and the cognitive roles of different subregions of larger brain areas.