Molecular genetic perspectives on cross-talk and specificity in abiotic stress signalling in plants
Molecular genetic perspectives on cross-talk and specificity in abiotic stress signalling in plants
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DOI：
10.1093/jxb/erh005
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发表时间：
2004-01-01
影响因子：
6.9
通讯作者：
Zhu, JK
中科院分区：
文献类型：
--
作者：
Chinnusamy, V;Schumaker, K;Zhu, JK
对非生物胁迫的感知和开启适应性反应的信号转导是确定暴露于不利环境的植物的生存和繁殖的关键步骤。植物具有针对胁迫的适应性反应以及保护植物免受多种环境胁迫的反应。压力感知和信号传导途径有多种，其中一些是特定的，但另一些可能在不同步骤中相互影响。最近，在识别与盐、干旱和冷胁迫相关的信号通路成分方面取得了进展。遗传分析定义了盐过度敏感（SOS）途径，其中盐胁迫诱导的钙信号可能被钙结合蛋白 SOS3 感知，然后激活蛋白激酶 SOS2。 SOS3-SOS2 激酶复合物调节 SOS1 等离子转运蛋白的表达和活性，以在盐度下重建细胞离子稳态。 ICE1（CBF表达诱导子1）-CBF（C-重复结合蛋白）途径对于冷响应转录组的调节和获得冷冻耐受性至关重要，尽管目前在冷应激期间激活ICE1转录因子的信号转导事件尚不清楚。 ABA 依赖性和独立性信号通路似乎都与渗透胁迫耐受性有关。丝裂原激活蛋白激酶 (MAPK) 级联的组成部分可能充当多种非生物和生物胁迫信号传导途径的汇聚点。正向和反向遗传分析与表达谱相结合将继续揭示许多信号传导成分，并且需要对信号传导复合物进行生化表征以确定非生物胁迫信号传导途径中的特异性和串扰。
The perception of abiotic stresses and signal transduction to switch on adaptive responses are critical steps in determining the survival and reproduction of plants exposed to adverse environments. Plants have stress-specific adaptive responses as well as responses which protect the plants from more than one environmental stress. There are multiple stress perception and signalling pathways, some of which are specific, but others may cross-talk at various steps. Recently, progress has been made in identifying components of signalling pathways involved in salt, drought and cold stresses. Genetic analysis has defined the Salt-Overly-Sensitive (SOS) pathway, in which a salt stress-induced calcium signal is probably sensed by the calcium-binding protein SOS3 which then activates the protein kinase SOS2. The SOS3-SOS2 kinase complex regulates the expression and activity of ion transporters such as SOS1 to re-establish cellular ionic homeostasis under salinity. The ICE1 (Inducer of CBF Expression 1)-CBF (C-Repeat Binding Protein) pathway is critical for the regulation of the cold-responsive transcriptome and acquired freezing tolerance, although at present the signalling events that activate the ICE1 transcription factor during cold stress are not known. Both ABA-dependent and -independent signalling pathways appear to be involved in osmotic stress tolerance. Components of mitogen-activated protein kinase (MAPK) cascades may act as converging points of multiple abiotic as well as biotic stress signalling pathways. Forward and reverse genetic analysis in combination with expression profiling will continue to uncover many signalling components, and biochemical characterization of the signalling complexes will be required to determine specificity and cross-talk in abiotic stress signalling pathways.