Experimental measurement and thermodynamic models for solid–liquid equilibrium of hyodeoxycholic acid in different organic solvents
Experimental measurement and thermodynamic models for solid–liquid equilibrium of hyodeoxycholic acid in different organic solvents
复制标题
猪去氧胆酸在不同有机溶剂中固液平衡的实验测量和热力学模型
DOI：
10.1016/j.molliq.2014.12.007
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发表时间：
2015-02
影响因子：
6
通讯作者：
沈飞
中科院分区：
文献类型：
--
作者：
杨洋;胡永红;张棋;程丽民;曹翠翠;杨文革;沈飞
Data on corresponding solid–liquid equilibrium of hyodeoxycholic acid (HDCA) in different solvents is essential for a preliminary study of industrial applications. In this paper, the solid–liquid equilibrium of HDCA in methanol, ethanol, isopropyl alcohol, butan-1-ol, ethyl acetate, acetone, acetonitrile, and acetic acid was explored at temperatures ranging from 278.15 to 333.15 K under atmosphere pressure. For the temperature range investigated, the solubility of HDCA in the solvents increased with increasing temperature. The modified Apelblat model, the Buchowski–Ksiazaczak λh model, and ideal model were adopted to describe and predict the change tendency of solubility. Besides, the calculated thermodynamic parameters indicated that in each studied solvent the dissolution process of HDCA is endothermic. Based on the analysis above, ethanol is considered to be the best solvent in crystallization process of HDCA.
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DOI：
10.3390/molecules180910497
发表时间：
2013-08-30
期刊：
Molecules (Basel, Switzerland)
影响因子：
--
作者：
Sabbatini P;Filipponi P;Sardella R;Natalini B;Nuti R;Macchiarulo A;Pellicciari R;Gioiello A
通讯作者：
Gioiello A
影响因子：
3.5
作者：
Bhat, Mashooq A.;Haq, Nazrul;Shakeel, Faiyaz
通讯作者：
Shakeel, Faiyaz
影响因子：
9.1
作者：
Zhichuan Shi;Zhigang Zhao;Xingli Liu;Yu Chen
通讯作者：
Zhichuan Shi;Zhigang Zhao;Xingli Liu;Yu Chen
影响因子：
2.6
作者：
Yumei Kai;Yonghong Hu;Tan Rongrong;Zhongbin Meng;Wenge Yang
通讯作者：
Yumei Kai;Yonghong Hu;Tan Rongrong;Zhongbin Meng;Wenge Yang
影响因子：
2.6
作者：
BUCHOWSKI, H;KHIAT, A
通讯作者：
KHIAT, A