Spectral analysis of the sleep onset period in primary insomnia
Spectral analysis of the sleep onset period in primary insomnia
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DOI：
10.1016/j.clinph.2013.10.010
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发表时间：
2014-05-01
影响因子：
4.7
通讯作者：
Ibanez, Vicente
中科院分区：
文献类型：
--
作者：
Cervena, Katerina;Espa, Fabrice;Ibanez, Vicente
目的：目的：比较睡眠发作性失眠（SOI）、睡眠维持性失眠（SMI）和睡眠良好者（GS）睡眠发作期（SOP）脑电功率谱特征（SOI患者：N = 10，SMI患者：N = 10，GS：N = 10）。结果：在入睡前，SOI患者β 2频段（18-29.75 Hz）的脑电功率明显低于SMI患者。睡眠开始前，SMI组的α功率显著高于GS组。尽管缺乏统计学显著性，但与其他两组相比，在SOI中观察到EEG动力学的几个差异：δ功率在睡眠开始后增加较慢; β 2和3（18-29.75和30-39.75 Hz）功率在睡眠开始前下降不太突然; β 1（15-17.75 Hz）功率在整个SOP中增加。SOI中β 2频段的较低水平以及δ和β频段的动力学差异可能表明，除了过度觉醒之外，还有其他机制参与了SOI的病因学。SOI。重要性：SOI和SMI患者在SOP中具有不同的光谱特征，因此未来的研究应避免纳入混合失眠样本。(C)2013年国际临床神经生理学联合会。由Elsevier爱尔兰有限公司出版。保留所有权利。
Objective: To compare the EEG power spectra characteristics of the sleep onset period (SOP) in patients with sleep onset insomnia (SOI), sleep maintenance insomnia (SMI) and good sleepers (GS).Methods: The time course of EEG power density (1-40 Hz) during the SOP was examined in thirty subjects (SOI patients: N = 10, SMI patients: N = 10, GS: N = 10).Results: The EEG power of the beta2 frequency band (18-29.75 Hz) was significantly lower in SOI than in SMI in the period preceding sleep onset. The alpha power was significantly higher for the SMI group compared to GS before sleep onset. Despite the lack of statistical significance, several differences in EEG dynamics were observed in SOI compared to two other groups: delta power increased slower after sleep onset; beta2 and 3 (18-29.75 and 30-39.75 Hz) power decrease less abruptly before sleep onset; beta1 (15-17.75 Hz) power increase through the whole SOP.Conclusions: The lower level of beta2 frequency band in SOI and the differences in dynamics in delta and beta bands may suggest that a mechanism other than hyperarousal participates in etiology of SOI. Significance: SOI and SMI patients have different spectral characteristics in SOP, thus future studies should avoid the inclusion of mixed insomnia samples. (C) 2013 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.