Two addic polysaccharides from the flowers of Chrysanthemum morifolium
Two addic polysaccharides from the flowers of Chrysanthemum morifolium
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DOI：
10.1080/1028602042000324880
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发表时间：
2006-04-01
影响因子：
1.7
通讯作者：
Fang, J.
中科院分区：
文献类型：
--
作者：
Zheng, Y.;Wang, X-S.;Fang, J.
从菊花中分离到两种新的酸性多糖F4和F5。单糖分析表明，F4含有阿拉伯糖、半乳糖和半乳糖醛酸单位，摩尔比为1.0:2.3:6.8，F5含有阿拉伯糖、鼠李糖半乳糖和半乳糖醛酸单位，摩尔比为1.0:3.2:1.0:4.3。甲基化分析、部分酸水解和核磁共振光谱分析结果表明，F4的半乳糖酸主链与阿拉伯半乳糖酸侧链与（1—> 3,4）链的3位相连，F5的鼠李糖主链与阿拉伯半乳糖酸侧链与（1—> 3,4）链的3位相连或鼠李糖与（1—> 2,4）链的4位相连。生物学实验显示F4和F5能模拟丝裂原诱导的T淋巴细胞和B淋巴细胞的体外增殖。
Two new acidic polysaccharides, F4 and F5, were isolated from the flowers of Chrysanthemum morifolium. Monosaccharide analysis indicated that F4 contained arabinose, galactose and galacturonic acid units in a molar ratio of 1.0:2.3:6.8 and F5 contained arabinose, rhamnose galactose and galacturonic acid units in a molar ratio of 1.0:3.2:1.0:4.3. The results of methylation analysis, partial acid hydrolysis and NMR spectral analysis indicated that F4 had a homogalacturonan main chain with arabinogalactan side chain linked to 3 position of (1 --> 3,4)-linked galacturonan and F5 had a rhamnogalacturonan main chain with arabinogalactan side chain linked to 3 position of (1 --> 3,4)-linked galacturonan or 4 position of (1 --> 2,4)-linked rhamnose. Biological tests revealed that F4 and F5 could simulate the mitogen induced T and B lymphocyte proliferation in vitro.