Denying the wolf access to sheep's clothing.
Denying the wolf access to sheep's clothing.
复制标题
不让狼接触到羊皮。
DOI：
10.1172/jci19417
复制
发表时间：
2003
期刊：
影响因子：
--
通讯作者：
Hoofnagle,JayH
中科院分区：
文献类型：
--
作者：
Heller,Theo;Hoofnagle,JayH
Hepatitis delta virus (HDV) is a cause of acute and chronic liver disease for which no effective therapy is currently available. Previous research has demonstrated that prenylation of the large HDV antigen is essential for viral assembly. A new report describes a novel small animal model for HDV replication and demonstrates that prenylation inhibitors are highly effective at clearing viremia and thus have potential relevance for the treatment of chronic delta hepatitis.
