Timely sleep facilitates declarative memory consolidation in infants
Timely sleep facilitates declarative memory consolidation in infants
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DOI：
10.1073/pnas.1414000112
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发表时间：
2015-02-03
影响因子：
11.1
通讯作者：
Schneider, Silvia
中科院分区：
文献类型：
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作者：
Seehagen, Sabine;Konrad, Carolin;Schneider, Silvia
人类婴儿将大部分时间用于睡眠。然而，人们对睡眠在早期记忆处理中的作用知之甚少。在这里，我们测试了6个月和12个月大的婴儿在4小时后对新动作的陈述性记忆[实验（Exp.）1]和24小时延迟（Exp. 2）。在午睡条件下的婴儿在学习后4小时内进行了延长的午睡（>= 30分钟），而在无午睡条件下的婴儿则没有。与年龄匹配的对照组进行比较发现，在两次延迟之后，只有在学习后小睡的婴儿才能记住测试中的目标动作。此外，在24小时的延迟后，婴儿在午睡条件下的记忆表现显着高于婴儿在nonap条件。这是我们所知的第一个实验证据，证明睡眠在巩固生命第一年的陈述性记忆中具有增强作用。
Human infants devote the majority of their time to sleeping. However, very little is known about the role of sleep in early memory processing. Here we test 6- and 12-mo-old infants' declarative memory for novel actions after a 4-h [Experiment (Exp.) 1] and 24-h delay (Exp. 2). Infants in a nap condition took an extended nap (>= 30 min) within 4 h after learning, whereas infants in a no-nap condition did not. A comparison with age-matched control groups revealed that after both delays, only infants who had napped after learning remembered the target actions at the test. Additionally, after the 24-h delay, memory performance of infants in the nap condition was significantly higher than that of infants in the nonap condition. This is the first experimental evidence to our knowledge for an enhancing role of sleep in the consolidation of declarative memories in the first year of life.