SYNERGISTIC EFFECT OF SILVER NANOPARTICLES WITH DOXYCYCLINE AGAINST KLEBSIELLA PNEUMONIA

SYNERGISTIC EFFECT OF SILVER NANOPARTICLES WITH DOXYCYCLINE AGAINST KLEBSIELLA PNEUMONIA
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纳米银颗粒与多西环素对抗肺炎克雷伯菌的协同作用

DOI:
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发表时间:
2016
期刊:
International Journal of Pharmacy and Pharmaceutical Sciences
影响因子:
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通讯作者:
S. Kaushik
S. Kaushik
中科院分区:
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文献类型:
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作者:
Nirmal Kumar;Satyajeet Das;A. Jyoti;S. Kaushik

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目的:纳米银(AgNPs)的绿色合成、表征及其与抗生素强力霉素对抗肺炎克雷伯菌的协同作用研究。方法:AgNps 由从石油土样品中分离的细菌合成。在对纳米颗粒进行表征后,研究了纳米颗粒的抗菌活性,同时将相同的纳米颗粒与多西环素抗生素联合使用。结果:观察到与AgNps和抗生素单独的作用相比,两者的集体作用更明显,这表明两种组分的协同作用。结论:这些发现强调了 AgNPs 增强多西环素抗生素对抗肺炎克雷伯菌感染活性的潜力。关键词:纳米银颗粒,绿色合成,肺炎克雷伯菌,强力霉素
Objective: Green synthesis, characterization of silver nanoparticles (AgNPs) and study of the synergistic effect of AgNPs with antibiotic doxycycline against Klebsiella pneumonia . Methods: AgNps were synthesized from bacteria isolated from samples obtained from petroleum soil. After characterization of the nanoparticles, the antibacterial activity of the nanoparticle was studied, and simultaneously the same nanoparticle was used in combination with doxycycline antibiotic. Results: It was observed that compared to the effects of AgNps and antibiotic alone, the collective effect on both of them was more evident, which indicate the synergistic effect of the two components. Conclusion: These findings highlight the potential for AgNPs to enhance the activity of doxycycline antibiotic against Klebsiella pneumonia infections. Keywords: Silver nanoparticle, Green Synthesis, Klebsiella Pneumonia , Doxycycline
DOI: 10.1016/j.electacta.2005.04.071
发表时间: 2005-11-10
影响因子: 6.6
作者:
Cho, KH;Park, JE;Park, SG
通讯作者: Park, SG