CNS embolism due to atrial myxoma: clinical features and diagnosis.
CNS embolism due to atrial myxoma: clinical features and diagnosis.
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DOI：
10.1001/archneur.1980.00500570033004
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发表时间：
1980-08
影响因子：
--
通讯作者：
B. Sandok;Irene von Estorff;E. R. Giuliani
中科院分区：
文献类型：
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作者：
B. Sandok;Irene von Estorff;E. R. Giuliani
本文分析了1957 ~ 1977年间经病理证实的40例心房粘液瘤。患者年龄范围为17至77岁;女性占主导地位，比例为3：1。35例患者患有左心房粘液瘤，3例患者患有右心房粘液瘤，1例患者患有双侧粘液瘤，1例患者患有右心房粘液瘤，随后切除了左心房粘液瘤。37例左心房粘液瘤患者中有10例（27%）至少发生1起神经系统事件，提示继发于栓塞的缺血。在大脑半球、脑干、小脑、视网膜和脊髓中观察到一过性或永久性缺血事件。虽然一些患者在初始评价时主要表现为神经系统事件，但心脏和全身症状占主导地位。超声心动图和扇形扫描为临床早期诊断提供了一种实用的方法。
The records of 40 patients with pathologically verified atrial myxoma identified during the period 1957 to 1977 were studied. The patients ranged in age from 17 to 77 years; women predominated by a ratio of 3:1. Thirty-five patients had left atrial myxoma, three patients had right atrial myxoma, one patient had bilateral myxomas, and one patient had a right atrial myxoma and subsequent removal of a left atrial myxoma. Ten of the 37 patients (27%) with left atrial myxoma had at least one neurologic event suggesting ischemia secondary to embolization. Transient or permanent ischemic events were noted in the cerebral hemispheres, brainstem, cerebellum, retina, and spinal cord. Although some patients were seen at the initial evaluation with primarily neurologic events, cardiac and constitutional symptoms dominated the clinical picture. Echocardiography and sector scanning provide a practical method for early clinical diagnosis.