Non-iterative numerical method for laterally superresolving Fourier domain optical coherence tomography

Non-iterative numerical method for laterally superresolving Fourier domain optical coherence tomography
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DOI:
10.1364/oe.14.001006
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发表时间:
2006-02-06
期刊:
影响因子:
3.8
通讯作者:
Yatagai, T
Yatagai, T
中科院分区:
物理与天体物理2区
文献类型:
--
作者:
Yasuno, Y;Sugisaka, JI;Yatagai, T

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提出了一种消除傅里叶域光学相干层析成像(FD-OCT)中横向散焦的数值解卷积方法。该方法利用深度相关的横向点扩散函数和一些近似设计用于消除横向散焦的反卷积滤波器。从理论上估计了横向分辨率的提高,并由此导出了横向超分辨在该方法中的作用。超分辨率的实验证实了剃刀刀片测试,并提出了一个直观的物理解释这种效果。剃刀刀片测试也证实,这种方法提高了OCT的信噪比。这种方法被应用到OCT图像的医学样本,在体内的人眼前节,并表现出其潜力,以消除实际OCT图像的散焦。讨论了用于设计反卷积滤波器的每个近似的有效性和限制。色和二维扩展的这种方法也被描述。(c)2006年美国光学学会。
A numerical deconvolution method to cancel lateral defocus in Fourier domain optical coherence tomography (FD-OCT) is presented. This method uses a depth-dependent lateral point spread function and some approximations to design a deconvolution filter for the cancellation of lateral defocus. Improved lateral resolutions are theoretically estimated; consequently, the effect of lateral superresolution in this method is derived. The superresolution is experimentally confirmed by a razor blade test, and an intuitive physical interpretation of this effect is presented. The razor blade test also confirms that this method enhances the signal-to-noise ratio of OCT. This method is applied to OCT images of medical samples, in vivo human anterior eye segments, and exhibits its potential to cancel the defocusing of practical OCT images. The validity and restrictions involved in each approximation employed to design the deconvolution filter are discussed. A chromatic and a two-dimensional extensions of this method are also described. (c) 2006 Optical Society of America.