Nanocarbons for DNA sequencing: A review
Nanocarbons for DNA sequencing: A review
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DOI：
10.1016/j.carbon.2017.01.012
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发表时间：
2017-05
期刊：
影响因子：
10.9
通讯作者：
N. Yang;Xin Jiang
中科院分区：
文献类型：
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作者：
N. Yang;Xin Jiang
利用纳米孔进行DNA测序，即所谓的纳米孔测序，是最有前途和最具革命性的DNA测序技术之一，它可以提供DNA分子中核碱基的顺序和类型。与现有的材料（如氮化硅、聚合物等）相比，纳米碳（如石墨烯、碳纳米管等）是纳米孔测序的完美材料。本文综述了纳米孔测序的一般问题，总结了利用石墨烯和碳纳米管进行纳米孔测序的最新进展和成果。展望了利用纳米碳进行纳米孔测序的未来研究方向。
DNA sequencing using nanopores, so-named nanopore sequencing, is one of the most promising and revolutionary DNA sequencing technologies to provide the order and the type of nucleobases in a DNA molecule. In compare to those existing materials (e.g., Si3N4, polymer, etc.), nanocarbons (e.g., graphene, carbon nanotubes, etc.) are perfect materials for nanopore sequencing. This article provides an overview on the general issues of nanopore sequencing and summarizes recent progress and achievements of nanopore sequencing using graphene and carbon nanotubes. The future research directions using nanocarbons for nanopore sequencing are discussed and outlined.