Combining in situ Generated Chiral Silicon Lewis Acid and Chiral Bronsted Acid Catalysts for [3+2]Cycloadditions: Cooperative Catalysis as a Convenient Enantioselective Route to Pyrazolidines
Combining in situ Generated Chiral Silicon Lewis Acid and Chiral Bronsted Acid Catalysts for [3+2]Cycloadditions: Cooperative Catalysis as a Convenient Enantioselective Route to Pyrazolidines
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DOI：
10.1002/adsc.201200293
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发表时间：
2012-11-01
影响因子：
5.4
通讯作者：
Tsogoeva, Svetlana B.
中科院分区：
文献类型：
--
作者：
Serdyuk, Olga V.;Zamfir, Alexandru;Tsogoeva, Svetlana B.
已经开发出一种通过[3+2]环加成反应轻松对映选择性合成手性吡唑烷的方法，该反应涉及BINOL衍生的磷酸和原位生成的BINOL磷酸盐衍生的硅路易斯酸，它们可以协同作用。
A facile enantioselective synthesis of chiral pyrazolidines via a [3+2]cycloaddition reaction, involving a BINOL-derived phosphoric acid and an in situ generated BINOL phosphate-derived silicon Lewis acid, which may act cooperatively, has been developed.