COMPUTER-SIMULATION OF ARTERIAL FLOW WITH APPLICATIONS TO ARTERIAL AND AORTIC STENOSES
COMPUTER-SIMULATION OF ARTERIAL FLOW WITH APPLICATIONS TO ARTERIAL AND AORTIC STENOSES
复制标题
DOI：
10.1016/0021-9290(92)90060-e
复制
发表时间：
1992-12-01
影响因子：
2.4
通讯作者：
ROGGE, TR
中科院分区：
文献类型：
--
作者：
STERGIOPULOS, N;YOUNG, DF;ROGGE, TR
建立了模拟人体动脉系统压力和血流传播的计算机模型。该模型基于一维流动方程，并考虑了几何和材料特性引起的非线性。55个动脉段，代表各种大动脉，被组合起来形成动脉系统的模型。特别注意在正常血流条件下和在动脉和主动脉狭窄条件下外周压力和血流脉冲的发展。结果表明，严重动脉狭窄的存在显著影响远端压力和血流脉冲的性质。主动脉狭窄对中央和外周压力脉冲的形成也有深远的影响。与已发表的实验数据比较表明，该模型能够较好地模拟正常血流条件下的动脉流动，以及狭窄性阻塞条件下的动脉流动。
A computer model for simulating pressure and flow propagation in the human arterial system is developed. The model is based on the one-dimensional flow equations and includes nonlinearities arising from geometry and material properties. Fifty-five arterial segments, representing the various major arteries, are combined to form the model of the arterial system. Particular attention is paid to the development of peripheral pressure and flow pulses under normal flow conditions and under conditions of arterial and aortic stenoses. Results show that the presence of severe arterial stenoses significantly affects the nature of the distal pressure and flow pulses. Aortic stenoses also have a profound effect on central and peripheral pressure pulse formation. Comparison with the published experimental data suggests that the model is capable of simulating arterial flow under normal flow conditions as well as conditions of stenotic obstructions in a satisfactory manner.