Effect of exposure to O3, NO2, and SO2 on chronic obstructive pulmonary disease hospitalizations in Tabriz, Iran
Effect of exposure to O3, NO2, and SO2 on chronic obstructive pulmonary disease hospitalizations in Tabriz, Iran
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DOI：
10.1007/s11356-014-3512-5
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发表时间：
2015-02-01
影响因子：
5.8
通讯作者：
Jaafari, Jalil
中科院分区：
文献类型：
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作者：
Ghozikali, Mohammad Ghanbari;Mosaferi, Mohammad;Jaafari, Jalil
城市空气污染是一个严重的环境问题，特别是在发展中国家。我们研究了伊朗西北部城市大不里士居民中气态污染物与慢性阻塞性肺疾病（COPD）住院之间的关系。我们使用了世界卫生组织（WHO）提出的方法，使用了世界卫生组织欧洲环境与健康中心Bilthoven分部开发的AirQ 2.2.3软件。为了评估人类接触臭氧和对健康的影响，臭氧数据被用作1小时平均值;二氧化氮和二氧化硫数据被用作每日平均浓度。采用AirQ 2.2.3模型评价空气污染与慢性阻塞性肺疾病（COPD）的关系。这项研究的结果表明，3%（95%CI 1.2- 4.8%）的HA COPD归因于O-3浓度超过10 μ g/m（3）。此外，0.9%（95% CI 0.1- 2.2%）和0.4%（95% CI 0- 1.1%）的HA COPD分别归因于NO2和SO2浓度超过10 μ g/m3。O-3、NO2和SO2浓度每增加10 μ g/m3，HA COPD的风险分别增加约0.58%、0.38%和0.44%。我们发现所有空气污染水平与COPD住院率之间存在显著正相关。否则，O-3、NO2和SO2对COPD住院有显着影响。
Air pollution in cities is a serious environmental problem especially in the developing countries. We examined the associations between gaseous pollutants and hospitalizations for chronic obstructive pulmonary diseases (COPD) among people living in Tabriz, a city in north western of Iran. We used the approach proposed by the World Health Organization (WHO) using the AirQ 2.2.3 software developed by the WHO European Center for Environment and Health, Bilthoven Division. To assess human exposure and health effect, data were used for ozone as a1h average; for nitrogen dioxide and sulfur dioxide as daily average concentrations. The association between air pollution and chronic obstructive pulmonary disease (COPD) was assessed using AirQ 2.2.3 model. The results of this study showed that 3 % (95 % CI 1.2-4.8 %) of HA COPD were attributed to O-3 concentrations over 10 mu g/m(3). Also, 0.9 % (95 % CI 0.1-2.2 %) and 0.4 % (95 % CI 0-1.1 %) of HA COPD were attributed to NO2 and SO2 concentrations over 10 mu g/m(3), respectively. For every 10 mu g/m(3) increase in O-3, NO2, and SO2 concentrations, the risk of HA COPD increase to about 0.58, 0.38, and 0.44 %, respectively. We found significant positive associations between the levels of all air pollution and hospital admissions COPD. Otherwise, O-3, NO2, and SO2 have a significant impact on COPD hospitalization.