Preanalytical and analytical factors affecting laboratory results
Preanalytical and analytical factors affecting laboratory results
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DOI：
10.3109/07853899809005854
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发表时间：
1998-06-01
影响因子：
4.4
通讯作者：
Grönroos, PE
中科院分区：
文献类型：
--
作者：
Irjala, KM;Grönroos, PE
实验室检查的结果对于疾病的诊断具有重要作用。然而，实验室结果并不总是与患者的临床状态相符。它们可能是出乎意料和令人惊讶的。另一方面，异常的实验室结果可能被接受并解释为疾病的征兆。然而，异常结果可能是由疾病以外的多种因素引起的。通常，这些干扰因素分为分析前因素和分析因素，此外还分为体内作用因素和体外作用因素。这些因素的清单很长而且很难记住。在这篇综述中，我们重点关注在实践中最常影响健康个体实验室结果并解释意外结果的因素。
The results of laboratory tests have a substantial role in the diagnostics of diseases. However, laboratory results do not always correspond with the patient's clinical status. They may be unexpected and surprising. On the other hand, an abnormal laboratory result may be accepted as such and interpreted as a sign of a disease. However, an abnormal result may result from several factors other than disease. Conventionally, these interfering factors have been divided into preanalytical and analytical factors and furthermore into factors acting in vivo and in vitro. The list of these factors is long and laborious to bear in mind. In this review we focus on the factors which, in practice, most often affect laboratory results in healthy individuals and which explain an unexpected result.