Role of nanobiotechnology in developing personalized medicine for cancer
Role of nanobiotechnology in developing personalized medicine for cancer
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DOI：
10.1177/153303460500400608
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发表时间：
2005-12-01
影响因子：
2.8
通讯作者：
Jain, KK
中科院分区：
文献类型：
--
作者：
Jain, KK
个性化医学简单地说就是最适合个人的特定疗法的处方。癌症治疗的个性化是基于在分子水平上更好地了解疾病。纳米技术将在这一领域发挥重要作用。纳米生物技术正被用于完善生物标志物的发现、分子诊断、药物发现和药物输送，这些都是个性化医学的重要基本组成部分，也适用于癌症的管理。举例说明了量子点、金纳米粒子和分子成像在诊断中的应用以及与治疗学的结合--个性化医学的另一个重要特征。个性化医疗开始得到认可，并有望在未来十年内成为医疗实践的一部分。在纳米生物技术的推动下，癌症的个性化管理有望使癌症能够及早发现，更有效和毒性更低的治疗增加了治愈的机会。
Personalized medicine simply means the prescription of specific therapeutics best suited for an individual. Personalization of cancer therapies is based on a better understanding of the disease at the molecular level. Nanotechnology will play an important role in this area. Nanobiotechnology is being used to refine discovery of biomarkers, molecular diagnostics, drug discovery and drug delivery, which are important basic components of personalized medicine and are applicable to management of cancer as well. Examples are given of the application of quantum dots, gold nanoparticles, and molecular imaging in diagnostics and combination with therapeutics - another important feature of personalized medicine. Personalized medicine is beginning to be recognized and is expected to become a part of medical practice within the next decade. Personalized management of cancer, facilitated by nanobiotechnology, is expected to enable early detection of cancer, more effective and less toxic treatment increasing the chances of cure.